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Evidence Synthesis in Healthcare Connect

Volume 1


open-access Systematic Review

Published: 21 Oct 2025

Prevalence of Helicobacter pylori Infection in India: A Systematic Review and Meta-Analysis

Volume 1

This study estimated the prevalence of H. pylori infection in India among adults and children with and without gastrointestinal (GI) disorders. This meta-analysis was conducted in accordance with the 2020 PRISMA guidelines and registered with PROSPERO (CRD42024597401). Scientific databases (e.g., MEDLINE, CINAHL, and Google Scholar) were searched to identify English-language articles from India presenting data on H. pylori prevalence. The quality of the included studies was assessed, and prevalence estimates..

open-access Systematic Review

Available Online: 17 Apr 2026

Mpox Clinical and Epidemiological Patterns in the Central African Republic: a Systematic Review and Meta-analysis

Volume 1

This study included 40 years evidences (1984-2024) describing the Mpox epidemiology, vaccination and clinical pattern in the Central African Republic (CAR), informing targeted control strategies for this re-emerging threat. This systematic review and meta-analysis followed the PRISMA guidelines. The searches   was conducted on PubMed, Scopus, ScienceDirect, Web of science, Embase, Cochrane Library, and AJOL. The random effect model was used to pooled estimates with R version 4.5.2. A p-value <0.05..

open-access Systematic Review

Available Online: 05 Feb 2026

Mpox varicella-zoster virus coinfection in the Democratic Republic of Congo: a systematic review and meta-analysis

Volume 1

Introduction: Monkeypox (Mpox) is an endemic disease in the Democratic Republic of Congo (DRC). After five decades of outbreaks, gaps still remain in understanding clinical patterns and coinfections with varicella-zoster virus (VZV) and human immunodeficiency virus (HIV) in this high-burden setting. This systematic review and meta-analysis were conducted to synthesize data on Mpox clinical presentation and coinfection trends in the Democratic Republic of the Congo. Estimating the burden of VZV..